Immunohistochemical localization of chondroitin sulphate and dermatan sulphate proteoglycans in tumour tissues
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چکیده
منابع مشابه
Structural variability of large and small chondroitin sulphate/dermatan sulphate proteoglycans.
Ledbetter, S. R., Tyree, B.. Hashell. J. R. & Horrigan. E. A. ( 1985) J . Biol. C'hrm. 260,8106-8 I 13 Hassell, J. R., Noonan, D. M., Ledbetter, S. R. & Laurie. G. W. (1986) C'ihri Found. Symp. 124,204-222 Noonan. D. M.. Horrigan. E. A.. Ledbetter. S. R.. Vogeli. G., Sasaki. M.. Yamada. Y. & Hassell. J . R. ( 1988) J . Riol. ('hem. 263, 16379-16387 Paulsson. M.. Yurchenko. P. D.. Ruben. G. C.. ...
متن کاملBovine aortic chondroitin sulphate- and dermatan sulphate-containing proteoglycans. Isolation, fractionation and chemical characterization.
1. Guanidinium chloride (4M) in the presence of proteinase inhibitors extracted 90% of bovine aorta galactosaminoglycans as proteoglycans that were subsequently purified by ion-exchange and gel chromatography. 2. Fractionation of the calcium salts of the purified proteoglycans with increasing concentration of ethanol yielded fractions PG-25 (28%), PG-35 (45%) and PG-50 (37%). 3. Fraction PG-50 ...
متن کاملStructure and properties of dermatan sulphate proteoglycans.
Introduction Fibrous connective tissues like sclera, skin, tendon and cornea have a high content of collagen but only small amounts of proteoglycans and structural glycoproteins. The specific blend of collagen and proteoglycan types determines the properties of the tissue. The proteoglycans are characterized by having a central protein core substituted by one or several glycosaminoglycan chains...
متن کاملZonal distribution of chondroitin-4-sulphate/dermatan sulphate and chondroitin-6-sulphate in normal and diseased human synovium.
OBJECTIVES Chondroitin sulphate is the major sulphated glycosaminoglycan present in the extracellular matrix of soft connective tissues and the aim of this study was to investigate the distribution of chondroitin sulphate species in normal and diseased synovium. METHODS Distribution of chondroitin-4-sulphate/dermatan sulphate (Ch4S/DS) and chondroitin-6-sulphate in normal (n = 6), osteoarthri...
متن کاملImmunochemical and biochemical comparisons between embryonic chick bone marrow and epiphyseal cartilage chondroitin/dermatan sulphate proteoglycans.
Chrondroitin sulphate proteoglycans obtained from embryonic chick bone marrow and epiphyseal cartilage were compared using immunochemical and biochemical analyses. Proteoglycans from each tissue, separated on CsCl density gradients, under dissociative conditions, into high (1.6 g ml-1), medium (1.5 g ml-1) and low (1.4 g ml-1) buoyant density fractions, were immunochemically analysed, using a p...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1988
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1988.12